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OneChoice Report

AI: ANTIMICROBIAL INTELLIGENCE
THERE'S NOTHING ARTIFICIAL ABOUT IT

The OneChoice Report is a revolution in patient care. Dozens of factors such as organisms, resistance genes, drug sensitivity, diagnosis codes, patient age, antibiotic allergies, renal function, pregnancy and more are all combined to reach a unique targeted and evidence-based treatment plan for each patient.

OneChoice makes real-time, evidence-based medicine a reality.

GET TO KNOW

Each element of the OneChoice® Report is carefully designed to increase ease of use and enhance patient care.

Hover over one of the highlighted hotspots to learn more about the features of the report.

THE INDUSTRY STANDARD
IN INFECTIOUS DISEASE GUIDANCE

Qualified Clinicians

Each recommendation is carefully reviewed by a team of high-level healthcare providers, including ID physicians, nurse practitioners and physician assistants– clinicians with actual patient experience who are licensed to prescribe medications

Antimicrobial Stewardship

OneChoice recommendations are proactive stewardship, helping ensure that the right antibiotic at the right dose for the right duration are prescribed at the right time– even alerting the prescriber when no antibiotic is necessary at all

PathFinder™

By identifying which organisms are likely pathogenic and the probable cause of infection and which resistant genes are relevant, treatment is targeted to ensure effective precision guided OneChoice recommendations

ARKSCORE™

Complex information is simplified using a color-coded numerical scale that allows providers to more accurately compare drug options and infection complexity

DOSADJUST™

Accurate and documented dosing targeted to the age bracket of the specific patient, whether they are neonates, infants, children, adolescents, or adults

Global Guidance™

Recommendations are available in any language and tailored to the unique drug formularies of specific regions or healthcare systems to accommodate global diversity

GET TO KNOW

Every report comes with easy access to an online version where you can delve deeper into the recommendations, access reference materials, translations, and additional dosing.

ArkScore™ helps prescribers make better-informed decisions by presenting complex information on a simple numerical scale. When faced with multiple patients, different lab results, and countless resistance genes, it can be difficult for prescribers to compare drug options or even the levels of infection complexity between patients.

The different ArkScore values combine Arkstone’s expertise in antimicrobial stewardship with complex algorithms and a deep understanding of infectious disease to help provide the most effective treatment, with the least risk for adverse events, reducing the unnecessary use of broad-spectrum antibiotics.

Infection Complexity Arkscore

provides a more complete picture to prescribers and caregivers of the level of difficulty presented by the detected organisms and resistance genes, when choosing a treatment plan.

Antimicrobial Resistance Arkscore

measures levels of antimicrobial resistance expressed in the detected organisms. Lower scores denote low resistance, in which case the antibiotic of choice can be given with less concern about adverse outcomes. A higher score indicates higher levels of resistance, limiting the antibiotic options available, increasing risk to the patient.

Adverse Reaction Arkscore

provides important information to the prescriber about the specific drug being recommended. The lower the score, the safer, more effective, and less risk associated with the use of that drug. The higher the score the more adverse events and risks to the patient associated with the antibiotic.

WE ARE TRUSTED BY WORLDS LEADING COMPANIES

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MEDICAL RESEARCH 90%
BIOTECHNOLOGY 80%

FREQUENTLY ASKED QUESTIONS

The first step in precision-guided patient care is determining which organisms detected in a lab result are most likely to be pathogenic, and therefore the highest value targets for treatment.

PathFinder™ uses proprietary algorithms, supervised machine learning and artificial intelligence to identify which organisms are more likely to be pathogenic and the cause of infection and the focus of the OneChoice treatment plans.

While a lab result may contain many detected organisms and resistance genes, their relevance can be different from sample to sample. For example, the same organism may be pathogenic if detected in a respiratory swab, but not in a urine sample. Likewise, certain detected resistance genes may not be relevant to the likely pathogens that need treatment, and therefore may not actually preclude certain treatment options.

The OneChoice Report and OneChoice Plus are intended to be used in conjunction.

The OneChoice Report is the provider’s inital source of information regarding the recommendations. But space on the page is limited, so expansive and interactive information and tools are available online via OneChoice PLUS.

Accessing OneChoice Plus is easy since each report includes a QR code link that will take clinicians directly to an online, interactive version of the report in their hands. OneChoice Plus allows clinicians to add or modify variables, like renal and hepatic function, allergies and pregnancy information, as well as accessing drug information, the MedsMatrix, literature references and NIH statistical data. The OneChoice Plus also has information pertaining to which resistance genes were tested for in a given sample, as well as information as to why an antibiotic may be precluded from use.

By using OneChoice Plus providers are able to make more informed decisions and get a broader understanding of the OneChoice recommendations.

OneChoice recommendations are based on published and accepted medical data. This includes Infectious Disease Society of America (IDSA) and the CDC guidelines. Antibiotic choices are based on intended use information on the FDA drug label.

Arkstone only references primary sources and does not rely on secondary sources such as treatment guides. The references used in determining treatment recommendations can be accessed via OneChoice Plus through the QR code on each report.

No. Research data has shown that infectious diseases physicians are the most qualified personnel for antimicrobial recommendations and stewardship. That’s why Arkstone uses human-in-the-loop machine learning, overseen by infectious disease clinicians and a highly trained multidisciplinary team, all of whom are licensed healthcare clinicians and prescribers.

Relying on pharmacists or other non-clinicians to make treatment recommendations can lead to mixed results for patients. Physicians are less likely to trust recommendations not made by a licensed practitioner. Additionally, non-clinicians lack the invaluable knowledge and experience that comes with treating patients in real world settings.

OneChoice is classified by the FDA as clinical decision support software (CDSS), intended to help prescribers make informed decisions.

Arkstone is not a laboratory. Arkstone analyzes data that laboratories obtain from specimens and is not involved in any of the processes the laboratory uses to determine if a specimen contains microbes or resistance genes.

Arkstone can work with any lab.

Arkstone integrates directly with laboratories through their laboratory information management system. Information is sent electronically to Arkstone after the laboratory has completely analyzed a specimen.